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← All Articles / Vein Health

Top Risk Factors for Developing Deep Vein Thrombosis

Divyang Ayar

Divyang Ayar

Board-Certified Vascular Specialist


September 22, 2025

Table Of Contents

32

Deep Vein Thrombosis, often just called DVT is something many people don’t think about until it becomes a serious health concern. It happens when a blood clot forms deep in the veins, usually in the legs, and it can quickly become dangerous if that clot travels to the lungs. That’s when it turns into a pulmonary embolism, a potentially life-threatening emergency.

Understanding the risk factors that contribute to DVT is more than just medical trivia, it’s a way to stay ahead of a condition that can sneak up on almost anyone. Whether someone is young and active or older and managing a chronic condition, being aware of the signs and risks can make all the difference.

Top Risk Factors for Developing DVT

While DVT can happen to anyone, there are certain situations and lifestyle factors that significantly increase the risk. Knowing what they are is the first step in prevention.

Prolonged Immobility

Sitting for long periods, like during a long-haul flight, a road trip, or extended bed rest after surgery or illness, can slow blood flow in the legs. When blood isn’t moving as it should, clots are more likely to form. For people who spend hours behind a desk or are recovering in bed, movement really matters.

Surgery and Trauma

Undergoing surgery, especially procedures involving the hips, knees, or abdomen, increases the risk of DVT. The combination of tissue injury and limited movement after surgery creates a perfect storm for blood clots. Even traumatic injuries like broken bones or major wounds can trigger clot formation during the healing process.

Age

As we age, our blood tends to thicken, and our vein health may decline. People over 60 have a naturally higher risk of DVT, but that doesn’t mean younger individuals are in the clear. Even those in their 20s or 30s can develop DVT, especially if other risk factors are present.

Family History and Genetic Clotting Disorders

Sometimes the risk is already written in the genes. Individuals with a family history of blood clots or who carry certain genetic mutations that affect blood clotting are more likely to develop DVT. These inherited conditions often go undiagnosed until a clot actually forms.

Obesity and Being Overweight

Excess weight puts additional pressure on veins, especially in the lower body. This pressure can slow down circulation, creating the ideal environment for clots to form. It’s not just about appearance; it’s about how weight affects the body’s internal systems.

Pregnancy and Postpartum Period

During pregnancy, the body naturally increases blood clotting to prepare for childbirth, which is helpful in the delivery room but risky in everyday life. Add the pressure of a growing uterus on pelvic veins and the reduced mobility that often comes with late pregnancy, and the risk of DVT increases. The danger doesn’t end after delivery either; the postpartum period carries its own elevated risk.

Hormonal Therapy or Birth Control Pills

Estrogen, found in many hormonal contraceptives and hormone replacement therapies, can increase clotting factors in the blood. For women who smoke, are overweight, or have other risk factors, hormonal medications can significantly amplify the risk of DVT.

Cancer and Cancer Treatments

Cancer changes the way the body handles clotting, and many treatments, including chemotherapy, further increase clot risk. Some tumors release substances that stimulate clotting, making people with certain cancers more vulnerable to developing DVT.

Smoking and Its Impact on Blood Clotting

Smoking damages blood vessels and thickens the blood. Over time, this can make it easier for clots to form. It’s not just the lungs and heart that take a hit from smoking; the entire circulatory system suffers.

Chronic Medical Conditions

Certain long-term health issues like heart disease, inflammatory bowel disease (such as Crohn’s or ulcerative colitis), and autoimmune disorders can all interfere with proper blood flow and clot regulation. People living with chronic illness often have multiple overlapping risks that make DVT more likely.

Tips to Reduce Your Risk of DVT

The good news is that many of these risk factors can be managed or even eliminated with a few mindful changes. Preventing DVT doesn’t require a complete lifestyle overhaul, just consistent, smart choices.

Stay Active and Move Regularly

One of the simplest things anyone can do is keep moving. Whether it’s standing up during a long flight, taking a walk every hour at work, or doing ankle rolls while watching TV, movement helps keep blood circulating the way it should.

Maintain a Healthy Weight

A balanced diet and regular exercise aren’t just for weight management, they directly improve blood flow and reduce pressure on the veins. Even small weight loss goals can make a noticeable difference.

Stay Hydrated

Dehydration can thicken the blood, increasing the risk of clotting. Drinking plenty of water throughout the day keeps blood flowing smoothly and supports overall vascular health.

Wear Compression Stockings If Recommended

For those who’ve had previous clots, are recovering from surgery, or are about to travel long distances, compression stockings can help prevent blood from pooling in the legs. They’re especially useful during recovery and long periods of sitting.

Follow Post-Surgery Recovery Guidelines Closely

After surgery, those early steps out of bed might feel daunting, but they’re crucial. Getting up and moving (as soon as it’s safe) is a key part of preventing post-op DVT. It’s also important to stick to any blood thinner or compression therapy your doctor recommends.

Quit Smoking and Limit Alcohol

Quitting smoking is one of the most impactful things anyone can do for their vascular health. It lowers the risk of not just DVT, but heart disease, stroke, and so much more. Limiting alcohol can also help, as excessive drinking may contribute to dehydration and affect clotting factors.

When to Seek a Doctor

Sometimes, the signs of DVT are subtle at first, but they shouldn’t be ignored. Knowing when to call a healthcare provider can prevent serious complications.

Persistent Leg Pain or Cramping

A dull ache or tightness in the calf that doesn’t go away might not be just a muscle strain. Pain that lingers or worsens should always be checked, especially if it appears without a clear reason.

Swelling, Redness, or Warmth in One Leg

If one leg suddenly becomes swollen, red, or warm to the touch, that’s a warning sign. It may mean a clot is forming and blocking normal blood flow.

Sudden Shortness of Breath, Chest Pain, or Coughing Up Blood

If a clot breaks off and travels to the lungs, it can cause a pulmonary embolism. This is a medical emergency. Any combination of sudden shortness of breath, sharp chest pain, or coughing up blood should be treated immediately.

Unexplained Rapid Heartbeat or Dizziness

Sometimes, a clot can affect more than just the leg. If someone experiences dizziness, fainting, or a racing heart without a clear reason, it could be linked to poor oxygen flow caused by a travelling clot.

Suffering From DVT? Contact Coastal Vascular Center

Deep Vein Thrombosis is serious, but it’s also often preventable. By understanding the risk factors, whether it’s a sedentary lifestyle, certain medications, or underlying health conditions, people can take action to protect themselves. Simple habits like staying active, keeping hydrated, and knowing the warning signs can go a long way in avoiding a potentially dangerous situation.

And when questions or concerns arise, it’s important to have a trusted team to turn to. At Coastal Vascular Centre, patients find not just advanced care, but compassionate professionals who are dedicated to the prevention, diagnosis, and treatment of vascular conditions like DVT. Whether it’s managing risk or navigating recovery, their expertise makes a lasting difference in keeping you healthy and informed every step of the way.



About the Author

Dr. Divyang C. Ayar

Dr. Divyang C. Ayar

Board-Certified Vascular Specialist

Dr. Ayar is a board-certified vascular and interventional radiologist serving patients in Pearland and Lake Jackson, TX. He specializes in minimally invasive treatments for peripheral arterial disease, vein conditions, uterine fibroids, and dialysis access.

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    Board Certified

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Coastal Vascular Center is Houston’s Arterial and Vein Treatment Center focusing on treatments of arterial disease, peripheral arterial disease, dialysis access management, spider veins, varicose veins, uterine fibroid embolization, interventional oncology and other venous related conditions and diseases.

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8619 Broadway St, STE 165
Pearland, Texas 77584
713-581-8621

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201 Oak Dr South, Suite 105
Lake Jackson, Texas 77566
979-300-7844

See Dr. Ayar's profile on Healthgrades.
Coastal Vascular Center - Logo

Coastal Vascular Center is Houston’s Arterial and Vein Treatment Center focusing on treatments of arterial disease, peripheral arterial disease, dialysis access management, spider veins, varicose veins, uterine fibroid embolization, interventional oncology and other venous related conditions and diseases.

  • Follow
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  • Follow

Quick Links

  • About Our Clinic
  • Book An Appointment
  • Testimonials
  • News
  • Lake Jackson
  • Pearland
  • Contact Us

Conditions

  • Arterial Ulcers
  • Claudication
  • Deep Vein Thrombosis
  • Dialysis Access Management
  • Gangrene
  • Leg Discoloration
  • Leg Swelling
  • Peripheral Arterial Disease
  • Spider Veins
  • Uterine Fibroid Embolization
  • Varicose Veins – Vein Reflux

Locations

Pearland Office

8619 Broadway St, STE 165
Pearland, Texas 77584
713-581-8621

Lake Jackson Office

201 Oak Dr South, Suite 105
Lake Jackson, Texas 77566
979-300-7844

See Dr. Ayar's profile on Healthgrades.
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