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← All Articles / PAD

Diabetes and Peripheral Artery Disease: Why Your Feet Are at Risk

Divyang Ayar

Divyang Ayar

Board-Certified Interventional Radiologist

June 17, 2026

Table Of Contents

32

If you have diabetes, your doctor has probably told you to check your feet every day. Many of my patients nod along, but they are not sure why it matters so much. The answer is that diabetes and peripheral artery disease are closely linked. Together, they can turn a small blister into a serious problem. In this article, I explain how the two conditions work together, which warning signs to watch for, and how we can protect your legs.

Key Takeaways

  • Diabetes speeds up plaque buildup in the leg arteries, so PAD often starts earlier and spreads to more areas.
  • Nerve damage from diabetes can hide the leg pain that usually warns of PAD.
  • A foot sore that has not improved in about two weeks needs prompt medical attention.
  • Good blood sugar, blood pressure, and cholesterol control, plus quitting smoking, help with both conditions.
  • Minimally invasive procedures such as angioplasty and stenting can restore blood flow and help wounds heal.

What Is Peripheral Artery Disease?

Peripheral artery disease, or PAD, happens when plaque narrows the arteries that carry blood to your legs and feet. This plaque is made of fat, cholesterol, and other substances. As a result, your muscles and skin get less oxygen. They also have a harder time healing after an injury.

Many people first notice cramping in the calves, thighs, or buttocks while walking. The pain usually eases after a few minutes of rest. Doctors call this claudication. However, many people with PAD have no symptoms at all for years.

How Diabetes and Peripheral Artery Disease Are Connected

Diabetes and PAD share many of the same risk factors. These include smoking, high blood pressure, high cholesterol, extra weight, inactivity, and family history. In addition, diabetes adds its own damage. According to the National Heart, Lung, and Blood Institute, diabetes is one of the main risk factors for PAD.

High Blood Sugar Damages Artery Walls

Over time, high blood sugar inflames and injures the inner lining of the blood vessels. Because of this, plaque builds up faster. In my patients with both conditions, I often find blockages in several places, especially in the smaller arteries below the knee. Those blockages are often harder to treat.

Nerve Damage Can Hide the Warning Signs

This is the part that worries me most. Diabetes often causes nerve damage, called neuropathy, in the feet and lower legs. If your nerves are damaged, you may not feel the leg pain that usually signals PAD. You may not notice a small cut or blister, either.

I have seen patients come in with a foot sore that will not heal. Then, when we look at their arteries, we find severe disease that has been growing quietly for years.

Slow Healing Can Become a Crisis

Every wound needs good blood flow to heal. With PAD, a minor blister, cut, or cracked callus may not get enough oxygen. With diabetes on top, that wound can become infected quickly. Over time, it can lead to arterial ulcers, gangrene, or even amputation. Fortunately, most of these outcomes can be prevented with early care.

Warning Signs You Should Never Ignore

Because neuropathy can mute pain, I ask my patients with diabetes to watch for signs they can see or feel with their hands:

  • A cut, blister, or sore that has not improved in about two weeks
  • Toes or feet that look pale, bluish, or darker than usual
  • Shiny, tight, or hairless skin on the lower legs or feet
  • One foot that feels colder than the other
  • Thick, slow-growing, or discolored toenails
  • Redness, swelling, or warmth around a wound
  • Cramping in the calves, thighs, or buttocks when you walk

The National Institute of Diabetes and Digestive and Kidney Diseases also recommends checking your feet every day. Use a mirror, or ask a family member to help.

How I Check for PAD in Patients With Diabetes

Since symptoms can be hidden, I take a proactive approach. First, I usually start with an ankle-brachial index test. This quick test compares the blood pressure in your ankle with the pressure in your arm.

However, diabetes can stiffen the arteries with calcium. That can make the ankle reading look normal even when blood flow is poor. For this reason, I often add a toe pressure test or a duplex ultrasound. Ultrasound lets me see blood flow in real time. Before any procedure, detailed imaging helps me map exactly where the blockages are.

Treating Diabetes and Peripheral Artery Disease Together

The good news is that steps that help one condition usually help the other. For most patients, treatment starts with:

  • Keeping blood sugar in the range your doctor recommends
  • Quitting smoking, which is the single most important change (read more about smoking and PAD)
  • Controlling blood pressure and cholesterol, often with a statin
  • Taking an antiplatelet medicine if your doctor prescribes one
  • Walking regularly to improve circulation
  • Wearing well-fitting shoes and never going barefoot

When blockages are more advanced, a minimally invasive procedure can restore blood flow. As an interventional radiologist, I work inside the artery through a tiny puncture. I may use angioplasty to open the artery with a small balloon. In some cases, I may also place a stent or remove plaque with atherectomy. Most patients go home the same day. In more complex cases, surgical bypass may be the better option, and I will refer you to a surgeon if so.

In every case, the goal is the same. We want to restore blood flow, heal wounds, and protect your leg.

When to Get Evaluated

You do not need to wait for a wound. I recommend an evaluation if you have diabetes and any of the following:

  • A sore on your foot or leg that is slow to heal
  • A sudden change in the color or temperature of one foot
  • Leg pain when walking, or foot pain at night
  • A history of smoking, high blood pressure, or high cholesterol
  • A past toe amputation or foot surgery
  • A family history of PAD or amputation

Managing diabetes and peripheral artery disease is a long-term team effort. Coastal Vascular Center is a small, locally owned practice, not a corporate chain. You will see me at every visit, and I personally perform every procedure. That continuity helps me spot small changes in your feet before they become big problems.

Protect Your Feet With Dr. Ayar

If you have diabetes and a slow-healing sore, leg pain, or changes in your feet, an evaluation is a simple first step. We will check your circulation and build a plan to protect your legs. You will see Dr. Ayar at every visit in Pearland or Lake Jackson.

Request an Appointment
Call 281-949-6020

About the Author

Dr. Divyang C. Ayar

Dr. Divyang C. Ayar

Board-Certified Interventional Radiologist

Dr. Ayar is a board-certified vascular and interventional radiologist serving patients in Pearland and Lake Jackson, TX. He specializes in minimally invasive treatments for peripheral arterial disease, vein conditions, uterine fibroids, and dialysis access.

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    Board Certified

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    20+ Years

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Coastal Vascular Center is Houston’s Arterial and Vein Treatment Center focusing on treatments of arterial disease, peripheral arterial disease, dialysis access management, spider veins, varicose veins, uterine fibroid embolization, interventional oncology and other venous related conditions and diseases.

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Locations

Pearland Office

8619 Broadway St, Suite 105
Pearland, Texas 77584

Lake Jackson Office

201 Oak Dr South, Suite 105
Lake Jackson, Texas 77566

281-949-6020

See Dr. Ayar's profile on Healthgrades.
Coastal Vascular Center - Logo

Coastal Vascular Center is Houston’s Arterial and Vein Treatment Center focusing on treatments of arterial disease, peripheral arterial disease, dialysis access management, spider veins, varicose veins, uterine fibroid embolization, interventional oncology and other venous related conditions and diseases.

  • Follow
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Quick Links

  • About Our Clinic
  • Book An Appointment
  • Testimonials
  • News
  • Lake Jackson
  • Pearland
  • Contact Us
  • Areas We Serve
  • Referrals

Conditions

  • Arterial Ulcers
  • Claudication
  • Deep Vein Thrombosis
  • Dialysis Access Management
  • Gangrene
  • Leg Discoloration
  • Leg Swelling
  • Peripheral Arterial Disease
  • Spider Veins
  • Uterine Fibroid Embolization
  • Varicose Veins – Vein Reflux

Locations

Pearland Office

8619 Broadway St, Suite 105
Pearland, Texas 77584

Lake Jackson Office

201 Oak Dr South, Suite 105
Lake Jackson, Texas 77566

281-949-6020

See Dr. Ayar's profile on Healthgrades.

Medical Disclaimer: The content on this website is for general informational purposes only and is not medical advice. It does not replace an evaluation by a qualified healthcare provider, and using this site or submitting a form does not create a doctor–patient relationship. Individual results vary. If you are having a medical emergency, such as sudden leg pain, a cold or discolored limb, or chest pain, call 911 or go to the nearest emergency room. Read our full Medical Disclaimer

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